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What special precautions should I follow?
Check the labels of all nonprescription (over-the-counter [OTC]) or prescription medicines you now take. If any contain a barbiturate or acetaminophen, check with your health care professional. Taking
them together with this medicine may cause an overdose.
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Possible Side Effect
If you experience any of the following serious side effects, stop taking acetaminophenbutalbitalcaffeine and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of yo
ur throat; swelling of your lips, tongue, or face; or hives); slow, weak breathing; liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, sev
ere fatigue); blood problems (easy or unusual bleeding or bruising); or low blood sugar (fatigue, increased hunger or thirst,
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Missed Dose
Take the missed dose as soon as you remember. Do not takedouble dose of Esgic . Wait the prescribed amount of time before taking your next dose.
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Significant Interactions:
Do not take acetamino phenbutalbital caffeine - Esgic if you have taken monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the las
t 14 days. Dangerous side effects could result. Acetaminophen and butalbital may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedative
s (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants.
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What Is It
Butalbital and acetaminophen (byoo-TAL-bi-tal and a-seat-a-MIN-oh-fen) combination is a pain reliever and relaxant. It is used to treat tension headaches. Butalbital belongs to the group of medicines
called barbiturates (bar-BI-tyoo-rates) . Barbiturates act in the central nervous system (CNS) to produce their effects.
When you take butalbital for a long time, your body may get used to i
t so that larger amounts are needed to produce the same effects. This is called tolerance to the medicine. Also, butalbital may become habit-forming (causing mental or physical dependence) when it is
used for a long time or in large doses. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.
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How should you take this medication?
The combination of acetaminophen, butalbital, and caffeine comes as a capsule and tablet to take by mouth. It usually is taken every 4 hours as needed. Follow the directions on your prescription label
carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take acetaminophen, butalbital, and caffeine exactly as directed. Do not take more than six tablets or capsules
in 1 day. If you think that you need more to relieve your symptoms, call your doctor.
This medication can be habit-forming. Do not take a larger dose, take it more often, or for a longer per
iod than your doctor tells you to.
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